Postdoctoral Research Fellow — Clonal Evolution and Genome Engineering in Inherited Bone Marrow Failure Disorders

A postdoctoral research associate position is available in the lab of Alyssa Kennedy. We are recruiting a postdoctoral fellow to study the mechanisms of clonal evolution and leukemic transformation in inherited bone marrow failure syndromes, with a focus on Shwachman-Diamond syndrome (SDS). The lab studies how somatic adaptation shapes disease trajectory, why certain clones are compensatory while others are pre-malignant, and whether therapeutic genome editing can shift that balance. Projects span primary patient samples, iPSC cell line models, CRISPR/base-editing screens, and single-cell genomics, with direct access to a clinical bone marrow failure program.…